Preface
Acknowledgements
Dedication
Part Ⅰ:Principles of Cell Biology and
Molecular Genetics
1. General Organization of the Cell
Prokaryotes and eukaryotes
Structure and function of eukaryotic organelles
Cell diversity in multicellular organisms
2. Proteins and Enzymes
Amino acids
Proteins
Enzymes
3. The Cell Membrane
Structure of the cell membrane
Transport across the cell membrane
Membrane potential
Receptors
4. The Working Cell
Cytoskeleton and cell motility
Lysosomes
Cell surface and cell adhesion
5. The Molecular Basis of Genetics
Organization of the cell nucleus
Cell cycle
Mitosis and meiosis
Nucleic acids
DNA packaging and repair
DNA replication
Transcription and RNA synthesis
Translation and protein synthesis
Control of gene expression and protein synthesis
Post-translational modification of proteins
Structure of genes
Genetics of bacteria and viruses
Part Ⅱ: Medical Genetics
6. Molecular Genetics as Applied to Medicine
Basic techniques of molecular
genetics
The human genome project
Cloning and characterizing human
disease genes
Gene therapy
7. Genetic Disease
Single gene disorders
Chromosomal disorders
Polygenic inheritance and multifactorial disorders
Genetics of cancer
8. Principles of Medical Genetics
Population genetics and screening
Risk assessment and genetic counselling
Genetic consultation and history taking
Common presentations of genetic disease
Part Ⅲ: Self-assessment
Multiple-choice Questions
Short-answer Questions
Essay Questions
MCQ Answers
SAQ Answers
Index
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